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Nearly five percent of all deaths in the U.S. are the result of malaria.

Date: 1850

DDD
EPD

For infants and the elderly, the percentage is much higher. Malaria is endemic across the United States in this era, especially in "warmer, wetter, and flatter" areas of the U.S. Risk for malaria is unequal, with increased prevalence along the Mississippi and Missouri valleys, as well as in counties with lower socioeconomic status.