U.S. and Peruvian doctors compare notes on the development of cocaine.
Date: 1860
Different coca leaf varieties are shared and sold back and forth between the U.S. and Peru, with a focus on the mass development of new products. One particular coca derivative, Erythroxylon coca, begins to be used as a tonic for the fast pace of urban life during the Gilded-Age and the resulting "American condition" of "neurasthenia," which manifests as nervousness.