What started as a plant, indigenous to India, South East Asia, and New Guinea, became a form of currency as precious as gold that demanded intensive labor for its cultivation. This story tracks the relationship between the greed for sugar profits, the decimation of indigenous lands, the creation of plantations, and the expansion of the North Atlantic Slave Trade. Focusing on the early colonization of the North American South, Hawai’i, and Puerto Rico, this story ends with the expansion of sugar production into multiple locations within the Global South. Sugar is a commodity that is still, in 2023, valued for the profit margins it creates at the expense of its impacts on the human body.