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Opiates become the go-to medicine when doctors are unsure what else to do.

Date: 1850

The Story of Opium
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Notes from a Louisiana doctor show that "opiates were administered, often in conjunction with other drugs, to treat such diverse conditions as asthma, bronchitis, cholera, chlorosis, colic, diarrhea, dysentery, hemorrhoids, intermittent fever, and leukorrhea" (Courtwright, 1983).